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Kraft, Andrew
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Academic Article Enforced expression of the Mr 33,000 Pim-1 kinase enhances factor-independent survival and inhibits apoptosis in murine myeloid cells.
Academic Article The PIM-1 serine kinase prolongs survival and inhibits apoptosis-related mitochondrial dysfunction in part through a bcl-2-dependent pathway.
Academic Article The PIM-2 kinase phosphorylates BAD on serine 112 and reverses BAD-induced cell death.
Academic Article Overexpression of the oncogenic kinase Pim-1 leads to genomic instability.
Academic Article Negative regulation of Pim-1 protein kinase levels by the B56beta subunit of PP2A.
Academic Article PIM1 protein kinase regulates PRAS40 phosphorylation and mTOR activity in FDCP1 cells.
Academic Article Novel benzylidene-thiazolidine-2,4-diones inhibit Pim protein kinase activity and induce cell cycle arrest in leukemia and prostate cancer cells.
Academic Article The Pim protein kinases regulate energy metabolism and cell growth.
Academic Article Pim kinase inhibitors sensitize prostate cancer cells to apoptosis triggered by Bcl-2 family inhibitor ABT-737.
Academic Article Abnormal hematopoietic phenotypes in Pim kinase triple knockout mice.
Academic Article Pim1 serine/threonine kinase regulates the number and functions of murine hematopoietic stem cells.
Academic Article Pim-1 protein kinase is nuclear in Burkitt's lymphoma: nuclear localization is necessary for its biologic effects.
Academic Article Elevation of receptor tyrosine kinases by small molecule AKT inhibitors in prostate cancer is mediated by Pim-1.
Academic Article A critical role for the cytoplasmic domain of the granulocyte-macrophage colony-stimulating factor alpha receptor in mediating cell growth.
Academic Article The kinase domain of Jak2 mediates induction of bcl-2 and delays cell death in hematopoietic cells.
Academic Article Pim family kinases enhance tumor growth of prostate cancer cells.
Academic Article Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases.
Academic Article A small molecule inhibitor of Pim protein kinases blocks the growth of precursor T-cell lymphoblastic leukemia/lymphoma.
Academic Article p53-dependent induction of prostate cancer cell senescence by the PIM1 protein kinase.
Academic Article Regulation of Skp2 levels by the Pim-1 protein kinase.
Concept Proto-Oncogene Proteins c-pim-1
Academic Article Deletion of Pim kinases elevates the cellular levels of reactive oxygen species and sensitizes to K-Ras-induced cell killing.
Academic Article The Pim-1 protein kinase is an important regulator of MET receptor tyrosine kinase levels and signaling.
Academic Article Metabolic dysfunction consistent with premature aging results from deletion of Pim kinases.
Academic Article The PIM family of oncoproteins: small kinases with huge implications in myeloid leukemogenesis and as therapeutic targets.
Academic Article Activation of Pim Kinases Is Sufficient to Promote Resistance to MET Small-Molecule Inhibitors.
Academic Article Regulation of prostate stromal fibroblasts by the PIM1 protein kinase.
Academic Article Insulin receptor substrate 1 is a substrate of the Pim protein kinases.
Academic Article Targeting the PIM protein kinases for the treatment of a T-cell acute lymphoblastic leukemia subset.
Academic Article PIM-2 protein kinase negatively regulates T cell responses in transplantation and tumor immunity.
Academic Article Targeting PIM Kinase with PD1 Inhibition Improves Immunotherapeutic Antitumor T-cell Response.
Academic Article PIM kinase (and Akt) biology and signaling in tumors.
Academic Article PIM Kinase Inhibitors Kill Hypoxic Tumor Cells by Reducing Nrf2 Signaling and Increasing Reactive Oxygen Species.
Academic Article Hypoxia-Inducible PIM Kinase Expression Promotes Resistance to Antiangiogenic Agents.
Academic Article Mechanisms Behind Resistance to PI3K Inhibitor Treatment Induced by the PIM Kinase.
Academic Article Phosphorylation of DEPDC5, a component of the GATOR1 complex, releases inhibition of mTORC1 and promotes tumor growth.
Academic Article PIM protein kinases regulate the level of the long noncoding RNA H19 to control stem cell gene transcription and modulate tumor growth.
Academic Article PIM Kinase Inhibitors Block the Growth of Primary T-cell Acute Lymphoblastic Leukemia: Resistance Pathways Identified by Network Modeling Analysis.
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  • Proto Oncogene Proteins c pim 1